Fragile X Syndrome

Evaluation and Treatment

EVALUATION

Boys (ages 18-48 months) with fragile X syndrome, developmental delays, or typical development are invited to participate in research examining cognitive and behavioral development as well as brain development in very young children.

Participation involves:

• 2-day cognitive and behavioral evaluation
• MRI of the brain

Benefits of participating:

• Free neuropsychological/educational evaluation including report
• $150 honorarium

Travel arrangements will be made by our research staff so that there will be no cost to families for participation. 

For more information contact Arianna Martin at ariannam@stanford.edu or (650) 724-2951.

PHARMACOLOGICAL TREATMENT

1. Individuals aged 14-30 years with fragile X syndrome are invited to participate in a medication trial using Aricept (donepezil). The goal of this study is to determine if enhancing cholinergic activity with Aricept has beneficial effects on behavior or cognition in individuals with fragile X syndrome.     

Participation involves:

• 3 visits to Stanford, spaced 3 weeks apart
• Daily dosage of Aricept
• Brief cognitive testing

For more information contact Amy Lightbody, Ph.D. alightbody@stanford.edu or (650) 724-2963.

1. Individuals aged 14-30 years with fragile X syndrome are invited to participate in a treatment study using intranasal Oxytocin (a natural hormone). The goal of this study is to determine if oxytocin augments social skills training for individuals with fragile X syndrome.     

Participation involves:

• 3 visits to Stanford, spaced 1 week apart
• Dosage of oxytocin during visits
• Eye contact training program
• Brief cognitive testing

For more information contact Scott Hall, Ph.D. hallss@stanford.edu or (650) 498-4799.

BEHAVIORAL TREATMENT

1. Girls aged 14-20 years with fragile X syndrome are invited to participate in a behavioral treatment program to improve functional math and money skills. The goal of this study is to determine if a computerized intensive stimulus equivalence program can improve functional skills in individuals with fragile X syndrome.     

Participation involves:

• 2 visits to Stanford, spaced 1 week apart
• Skills training on the computer
• Home-based practice
• Brief cognitive testing
• fMRI scan

For more information contact Scott Hall, Ph.D. hallss@stanford.edu or (650) 498-4799.

To participate in any of these studies, or if you would like to join our Research Registry to be contacted about future studies, please call toll free 1-888-411-BNRC (2672).